The important distinction between hemophagocytic lymphohistiocytosis and enteroviral infection

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Enteroviral infection is the most frequently diagnosed viral infection among newborns and is treated according to its severity. Hemophagocytic lymphohistiocytosis (HLH) is a rare but fatal disorder of an exaggerated immune response, treated with chemotherapy or immunosuppressive agents. Because HLH is so rare, it should only be diagnosed with great care in newborn patients displaying enteroviral infection

A new scoring system can help doctors predict future neurological deficits in newborns who experience seizures

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Medical advances have allowed more newborns experiencing seizures to survive into adulthood than ever before. Early identification of children likely to develop developmental disorders following neonatal seizures will allow for early treatment, which can minimize eventual cognitive and motor delays.

Removing Barriers for Youth with Physical Disabilities Increases Participation

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This study aimed to gain more insight into the effectiveness of altering the environment in which youth with physical disabilities participate in leisurely activities in Quebec.

Benefits and drawbacks of using genomic discoveries for autism spectrum disorder

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This article is a summary of significant advances in evidence-based practices related to ASD diagnosis, characterization, and treatment. It includes a discussion on the scientific, ethical, policy, and communication aspects of translating new discoveries into clinical and diagnostic tools.

Sensori-motor performance and daily living skills in preschool children with autism

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Early interventions that address sensory and motor development may facilitate a child’s integration into daycare programs and schools and ease the burden of care for parents.

The ASD Demonstration Project: A multi-center study to expand our understanding of ASD

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NeuroDevNet hopes that the ASD Demonstration Project will improve clinical care and the daily lives of individuals with ASD and their families by promoting earlier diagnoses, concrete prognoses, and individually targeted treatments.

Identifying new genetic markers associated with autism spectrum disorders

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This study adds 6 potential target loci to the list of genetic mutations that are associated with ASD. Continuing study of important genetic markers will help scientists develop earlier outcome prediction and therapeutic intervention in children with ASDs.

Mutations in the foxp1 gene may be associated with language impairments that accompany intellectual disability and autism

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The FOXP1 and FOXP2 genes provide interesting genetic targets for further investigation into the molecular mechanisms underlying neurodevelopmental disorders like intellectual disability, ASD, and language impairment.

Can administrative databases such as the RAMQ be used to identify children with traumatic brain injury?

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Combining patient information into a physician billing claim data-base (the ramq database), which is readily available, may be a valid method of estimating injury occurrence among children.

Do children who sustain a mild traumatic brain injury lose confidence in returning to physical activity?

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Some children, after a mild traumatic brain injury, appear to lack confidence in their ability to perform well during physical activities as compared to before their injury. This occurs even though the children are still participating in physical activities at comparable levels to before injury.

Do children with mild traumatic brain injury comply with activity restrictions given to them by health professionals?

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This article shows us that children with mild traumatic brain injury do a good job of complying with the activity restrictions given to them by health care professionals. This finding is a stepping stone for further studies looking at the effectiveness of restricting activity for better recovery from MTBI.

Is there an effective rehabilitation program to help children who are slow to recover from a sports- related concussion?

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A gradual, closely-supervised active rehabilitation program provides not only means to a faster recovery, but also, qualitatively speaking, increases the self-efficacy and confidence of the child, as well as the empowerment of the parents.

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